Oestradiol patch efficacy concerns

We understand that there are concerns about the efficacy and adhesion of some batches of Estradot (oestradiol) patches.

Medsafe have been investigating the concerns raised.

• Information about the Medsafe process can be found here: 

• Information from the supplier of Estradot, Sandoz can be found here:   

We have sent communications to consumer groups advising:

• Pharmac is responsible for the funding of medicines, while Medsafe assesses medicines to ensure they meet internationally agreed standards for safety, quality, and efficacy

• Any concerns about the efficacy of a batch of Estradot patches should be reported to Medsafe. These concerns can also be reported to the supplier, Sandoz.

• Estradiol TDP Mylan patches are available. Other treatment options such as oestradiol gel or tablets are available but would require a new prescription

• If patients experience any changes in health or have health concerns relating to their condition, they should see their prescriber.

Please share this information with your networks

You can find more information on oestradiol patches on the Pharmac website here.

Please contact enquiries@pharmac.govt.nz if you have any questions about this change.

Ngā mihi

Pharmac Implementation Team

Pharmac Implementation Team

Pharmac | Te Pātaka Whaioranga | PO Box 10 254 | Level 9, 40 Mercer Street, Wellington

P: 0800 660 050 | www.pharmac.govt.nz

Pharmac will be closed over the Christmas break from Thursday 25 December 2025, reopening Monday 5 January 2026.